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Los niveles de troponina pueden seguir aumentando durante aproximadamente 24 horas después de comenzar un ataque al corazón. Por ello, si los resultados de su prueba muestran niveles altos de troponina, es possible que le hagan la prueba dos o más veces en un período de 24 horas.

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Improved analytical sensitivity in the newer assays will permit extra fast and simpler rule-in and rule-out methods. Since the newer, additional analytically sensitive troponin assays are available in The usa, clinicians will require to rethink how they get and interpret troponin tests. Higher comprehension of the assay's functioning properties could lead to much more proper purchasing procedures and improved diagnostic accuracy for sufferers presenting with suspected acute MI.

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Early assays for cTnI and cTnT had been comparatively insensitive. Only large concentrations may be detected from the circulation. This led into the thought that troponin launch from the myocardium only occurred soon after sizeable ischaemic damage. The detection of troponins within the blood became Nearly synonymous with acute coronary syndrome. Even scatter hitam so, newer assays are roughly 1000-fold much more sensitive so they can detect troponins in people without ischaemia. Low concentrations can be detected in the circulation in nutritious people today in the course of lifetime, and Just about all children from in the vicinity of puberty have detectable cTnI of deposit pulsa their blood.

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implies that the assays have Substantially reduce boundaries of detection, enabling quantification of troponin at concentrations which were undetectable with earlier assays. Importantly, reducing the limits of detection for an assay can have no impact on the 99th percentile Slice-point that determines the upper limit of the normal selection.

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